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BRD4 Inhibitor-10

Name: BRD4 Inhibitor-10
Brand: TargetMol
SKU: T14776
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T14776Cas No. 1660117-38-3

BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).

BRD4 Inhibitor-10

🥰Excellent

Purity: 99.53%

Catalog No. T14776Cas No. 1660117-38-3

BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).

Pack Size	Price	Availability
1 mg	$39	In Stock
5 mg	$98	In Stock
10 mg	$158	In Stock
25 mg	$317	In Stock
50 mg	$461	In Stock
100 mg	$648	In Stock
200 mg	$873	In Stock
1 mL x 10 mM (in DMSO)	$107	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.53%

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
Targets&IC50	BRD4 BD1:8 nM

Chemical Properties

Molecular Weight	429.51
Formula	C₂₅H₂₇N₅O₂
Cas No.	1660117-38-3
Smiles	C[C@@H](c1ccccc1)n1c(nc2cnc(cc12)C1CCOCC1)-c1cc(C)c(=O)n(C)n1
Relative Density.	1.30 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (291.03 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (9.31 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3282 mL	11.6412 mL	23.2823 mL	116.4117 mL
5 mM	0.4656 mL	2.3282 mL	4.6565 mL	23.2823 mL
10 mM	0.2328 mL	1.1641 mL	2.3282 mL	11.6412 mL
20 mM	0.1164 mL	0.5821 mL	1.1641 mL	5.8206 mL
50 mM	0.0466 mL	0.2328 mL	0.4656 mL	2.3282 mL
100 mM	0.0233 mL	0.1164 mL	0.2328 mL	1.1641 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc