store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JMS-053 is a potent and selective inhibitor of the phosphatase DUSP3, inhibits PTP4A3, PTP4A1, PTP4A2 and CDC25B, inhibits cancer cell migration and sphere growth, and avoids disruption of the microvascular endothelial barrier by vascular endothelial growth factor or lipopolysaccharide.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 230.00 |
Description | JMS-053 is a potent and selective inhibitor of the phosphatase DUSP3, inhibits PTP4A3, PTP4A1, PTP4A2 and CDC25B, inhibits cancer cell migration and sphere growth, and avoids disruption of the microvascular endothelial barrier by vascular endothelial growth factor or lipopolysaccharide. |
Targets&IC50 | PTP4A2:48.0 nM, PTP4A3:34.7 nM, CDC25B:92.6 nM, PTP4A1:29.1 nM, DUSP3:207.6 nM |
Molecular Weight | 256.28 |
Formula | C13H8N2O2S |
CAS No. | 1954650-11-3 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL (19.51 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JMS-053 1954650-11-3 Metabolism Phosphatase inhibitor inhibit