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Uniconazole

Name: Uniconazole
Brand: TargetMol
SKU: T21482
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21482Cas No. 83657-22-1

Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM). CYP707As is a major ABA catabolic enzyme that catabolize Abscisic acid, accordingly suppress gibberellin and sterol biosynthesis.

Uniconazole

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Purity: 99.94%

Catalog No. T21482Cas No. 83657-22-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$35	In Stock	In Stock
5 g	$81	-	In Stock
10 g	$118	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.94%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Uniconazole AI Summary

Uniconazole exhibits bioactivities that include the inhibition of rice stem elongation and cress growth, as well as acting as a small molecule agonist in various signaling pathways. In the rice stem elongation test, the compound showed inhibitory effects with a stem length measuring at 1.4 cm after 7 days. In the cress growth assays, different concentrations of the compound resulted in inhibitory effects on hypocotyl length, measuring from 0.5 cm to 1.0 cm. In addition, Uniconazole demonstrates high potency in the farnesoid X receptor signaling pathway with a value of 1.0 nM. It also shows potency of 68589.6 nM in the antioxidant response element (ARE) signaling pathway. Furthermore, the compound acts as an activator in the rat pregnane X receptor (rPXR) and human pregnane X receptor (PXR) signaling pathways with potencies of 10000.0 nM and 11220.2 nM, respectively..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM). CYP707As is a major ABA catabolic enzyme that catabolize Abscisic acid, accordingly suppress gibberellin and sterol biosynthesis.
Targets&IC50	CYP707A:68 nM (ki)

Chemical Properties

Molecular Weight	291.78
Formula	C₁₅H₁₈ClN₃O
Cas No.	83657-22-1
Smiles	CC(C)(C)C(O)C(=C/c1ccc(Cl)cc1)\n1cncn1
Relative Density.	1.18 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (154.23 mM), Sonication is recommended.

H2O: < 0.1 mg/mL (insoluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.85 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4272 mL	17.1362 mL	34.2724 mL	171.3620 mL
5 mM	0.6854 mL	3.4272 mL	6.8545 mL	34.2724 mL
10 mM	0.3427 mL	1.7136 mL	3.4272 mL	17.1362 mL
20 mM	0.1714 mL	0.8568 mL	1.7136 mL	8.5681 mL
50 mM	0.0685 mL	0.3427 mL	0.6854 mL	3.4272 mL
100 mM	0.0343 mL	0.1714 mL	0.3427 mL	1.7136 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc