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LY 344864

Name: LY 344864
Brand: TargetMol
SKU: T2344
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2344Cas No. 186544-26-3

Alias LY344864

LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.

LY 344864

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Purity: 98%

Catalog No. T2344Alias LY344864Cas No. 186544-26-3

LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.

Pack Size	Price	Availability
2 mg	$34	In Stock
5 mg	$55	In Stock
10 mg	$89	In Stock
25 mg	$169	In Stock
50 mg	$312	In Stock
100 mg	$555	In Stock
1 mL x 10 mM (in DMSO)	$61	In Stock

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Purity:98%

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COA HPLC

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Product Introduction

Bioactivity

Description	LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.
Targets&IC50	5-HT1F:6 nM, 5-HT3A Receptor (human):3.935 mM (Ki), 5-HT1D receptor (human):0.575 μM (Ki), 5-HT7 receptor (human):4.851 μM (Ki), human 5-HT 1E Receptor:1.415 μM (Ki), 5-HT1B receptor (human):0.549 μM (Ki), 5-HT2B receptor (human):1.695 μM (Ki), human 5-HT 1F Receptor:0.006 μM (Ki), 5-HT2A receptor (human):3.499 μM (Ki), 5-HT1A receptor (human):0.530 μM (Ki), α2 adrenergic receptor (rat):3.69 μM (Ki), α1 adrenergic receptor (rat):5.06 μM (Ki)
Alias	LY344864

Chemical Properties

Molecular Weight	351.42
Formula	C₂₁H₂₂FN₃O
Cas No.	186544-26-3
Smiles	Cl.CN(C)[C@@H]1CCc2[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc3c2C1
Relative Density.	1.28 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: >10 mM, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8456 mL	14.2280 mL	28.4560 mL	142.2799 mL
5 mM	0.5691 mL	2.8456 mL	5.6912 mL	28.4560 mL
10 mM	0.2846 mL	1.4228 mL	2.8456 mL	14.2280 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc