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SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitor with an IC50 value of 26.4 μM for SIRT5 and no inhibitory effect on SIRT1/2/3 isoforms at 400 μM, with anticancer potential.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $722 | In Stock | |
10 mg | $987 | In Stock | |
25 mg | $1,520 | In Stock | |
50 mg | $1,980 | In Stock | |
100 mg | $2,500 | In Stock |
Description | SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitor with an IC50 value of 26.4 μM for SIRT5 and no inhibitory effect on SIRT1/2/3 isoforms at 400 μM, with anticancer potential. |
Targets&IC50 | SIRT5:26.4 μM |
In vitro | SIRT5 inhibitor 4 was identified as a selective SIRT5 inhibitor (IC₅₀ = 26.4 ± 0.8 μM) with no inhibition on SIRT1–3[1]. |
Molecular Weight | 369.39 |
Formula | C18H15N3O4S |
Cas No. | 708992-34-1 |
Smiles | O=C(O)C1=CC=C(C=C1O)NC2=NC(=CS2)C=3C=CC(=CC3)NC(=O)C |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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