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Rasagiline

Name: Rasagiline
Brand: TargetMol
SKU: T1119
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1119Cas No. 136236-51-6

Alias TVP1012, AGN1135

Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.

Rasagiline

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Purity: 99.87%

Catalog No. T1119Alias TVP1012, AGN1135Cas No. 136236-51-6

Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.

Pack Size	Price	Availability
10 mg	$34	In Stock
25 mg	$55	In Stock
50 mg	$80	In Stock
100 mg	$105	In Stock
200 mg	$142	In Stock
500 mg	$236	Backorder
1 mL x 10 mM (in DMSO)	$39	In Stock

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Purity:99.87%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.
Targets&IC50	MAO-A:412 nM, MAO-B:4.43 nM
Synonyms	TVP1012, AGN1135

Chemical Properties

Molecular Weight	171.24
Formula	C₁₂H₁₃N
Cas No.	136236-51-6
Smiles	C#CCN[C@@H]1CCC2=C1C=CC=C2
Relative Density.	1.05 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 23.4 mM, Sonication is recommended.

DMSO: 50 mg/mL (291.99 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (11.68 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.8398 mL	29.1988 mL	58.3976 mL	291.9879 mL
5 mM	1.1680 mL	5.8398 mL	11.6795 mL	58.3976 mL
10 mM	0.5840 mL	2.9199 mL	5.8398 mL	29.1988 mL
20 mM	0.2920 mL	1.4599 mL	2.9199 mL	14.5994 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.1168 mL	0.5840 mL	1.1680 mL	5.8398 mL
100 mM	0.0584 mL	0.2920 mL	0.5840 mL	2.9199 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc