Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SIRT2-IN-9 is a selective SRIT2 inhibitor with an IC50 value of 1.3 μM.SIRT2-IN-9 inhibits the proliferation of MCF-7 breast cancer cells.SIRT2-IN-9 can be used for cancer research.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 118.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 392.00 | |
100 mg | In stock | $ 588.00 |
Description | SIRT2-IN-9 is a selective SRIT2 inhibitor with an IC50 value of 1.3 μM.SIRT2-IN-9 inhibits the proliferation of MCF-7 breast cancer cells.SIRT2-IN-9 can be used for cancer research. |
Targets&IC50 | SIRT2:1.3 μM |
In vitro |
SIRT2-IN-9 (1-100 μM; 15 min) dose-dependently inhibits SRIT2 (IC50=1.3 μM), and inhibits SRIT1 and SRIT3 (IC50s>300 μM).[1] SIRT2-IN-9 (0-50 μM; 72 h) affects the cell viability of MCF-7 cells and dose-dependently inhibited cell proliferation of MCF-7 breast cancer cells.[1] SIRT2-IN-9 (0-50 μM; 6 h) affects acetylation of α-tubulin protein.[1] |
Molecular Weight | 438.57 |
Formula | C21H22N6OS2 |
CAS No. | 522650-91-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.0 mg/mL (9.2 mM), Sonication and heating to 70℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SIRT2-IN-9 522650-91-5 Chromatin/Epigenetic DNA Damage/DNA Repair Sirtuin inhibitor inhibit