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AMT hydrochloride

Name: AMT hydrochloride
Brand: TargetMol
SKU: T22569
Rating: 4.5 (1 reviews)

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Catalog No. T22569Cas No. 21463-31-0

AMT hydrochloride is a potent, selective, and reversible inhibitor of inducible nitric oxide synthase (iNOS) with an IC50 of 3.6 nM, showing approximately 30-fold and 40-fold selectivity over nNOS and eNOS respectively, AMT hydrochloride is extensively used in inflammation, immunology, and cardiovascular research to dissect nitric oxide–mediated pathological processes.

AMT hydrochloride

😃Good

Catalog No. T22569Cas No. 21463-31-0

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$223	35 days	35 days
10 mg	$395	35 days	35 days
50 mg	$1,620	35 days	35 days
100 mg	$2,560	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	166.67
Formula	C₅H₁₁ClN₂S
Cas No.	21463-31-0
Smiles	Cl.N1=C(SC(C)CC1)N
Relative Density.	1.31 g/cm3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Soluble

DMSO: 40 mg/mL (240 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.9999 mL	29.9994 mL	59.9988 mL	299.9940 mL
5 mM	1.2000 mL	5.9999 mL	11.9998 mL	59.9988 mL
10 mM	0.6000 mL	2.9999 mL	5.9999 mL	29.9994 mL
20 mM	0.3000 mL	1.5000 mL	2.9999 mL	14.9997 mL
50 mM	0.1200 mL	0.6000 mL	1.2000 mL	5.9999 mL
100 mM	0.0600 mL	0.3000 mL	0.6000 mL	2.9999 mL

Calculator

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Dilution Calculator
Reconstitution Calculator
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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc