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Midecamycin

Name: Midecamycin
Brand: TargetMol
SKU: T5037
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T5037Cas No. 35457-80-8

Alias Turimycin P3, Rubimycin, Platenomycin B1, Medecamycin A1, Espinomycin A, Antibiotic SF-837

Midecamycin (Medecamycin A1), an acetoxy-substituted macrolide antibiotic, has effective on gram-positive and gram-negative bacteria acts by inhibiting bacterial protein synthesis.

Midecamycin

🥰Excellent

Purity: 98.84%

Catalog No. T5037Alias Turimycin P3, Rubimycin, Platenomycin B1, Medecamycin A1, Espinomycin A, Antibiotic SF-837Cas No. 35457-80-8

Midecamycin (Medecamycin A1), an acetoxy-substituted macrolide antibiotic, has effective on gram-positive and gram-negative bacteria acts by inhibiting bacterial protein synthesis.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$31	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.84%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Midecamycin (Medecamycin A1), an acetoxy-substituted macrolide antibiotic, has effective on gram-positive and gram-negative bacteria acts by inhibiting bacterial protein synthesis.
In vitro	Midecamycin, a novel 16-membered macrolide antibiotic produced by Streptomyces mycarofaciens, effectively inhibits a substantial portion of streptococci, staphylococci, and strains of Haemophilus and Listeria at concentrations below 3.1 μg/mL [1] [2].
Synonyms	Turimycin P3, Rubimycin, Platenomycin B1, Medecamycin A1, Espinomycin A, Antibiotic SF-837

Chemical Properties

Molecular Weight	813.97
Formula	C₄₁H₆₇NO₁₅
Cas No.	35457-80-8
Smiles	O([C@@H]1[C@@H](OC)[C@H](OC(CC)=O)CC(=O)O[C@H](C)C\C=C\C=C/[C@H](O)[C@H](C)C[C@@H]1CC=O)[C@H]2[C@H](O)[C@@H](N(C)C)[C@H](O[C@H]3C[C@@](C)(O)[C@@H](OC(CC)=O)[C@H](C)O3)[C@@H](C)O2
Relative Density.	1.21g/cm3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (73.71 mM), Sonication is recommended.

Ethanol: 50 mg/mL (61.43 mM), Sonication is recommended.

H2O: Insoluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.46 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2285 mL	6.1427 mL	12.2855 mL	61.4273 mL
5 mM	0.2457 mL	1.2285 mL	2.4571 mL	12.2855 mL
10 mM	0.1229 mL	0.6143 mL	1.2285 mL	6.1427 mL
20 mM	0.0614 mL	0.3071 mL	0.6143 mL	3.0714 mL
50 mM	0.0246 mL	0.1229 mL	0.2457 mL	1.2285 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc