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Temgicoluril

Name: Temgicoluril
Brand: TargetMol
SKU: T9424
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9424Cas No. 10095-06-4

Alias Tetramethylglycoluril, mebikar

Temgicoluril (mebikar) acts on GABA Receptor.

Temgicoluril

🥰Excellent

Purity: 99.8%

Catalog No. T9424Alias Tetramethylglycoluril, mebikarCas No. 10095-06-4

Temgicoluril (mebikar) acts on GABA Receptor.

Pack Size	Price	Availability	Quantity
25 mg	$29	In Stock

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Purity:99.8%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Temgicoluril (mebikar) acts on GABA Receptor.
Synonyms	Tetramethylglycoluril, mebikar

Chemical Properties

Molecular Weight	198.22
Formula	C₈H₁₄N₄O₂
Cas No.	10095-06-4
Smiles	CN1C2C(N(C)C1=O)N(C)C(=O)N2C
Relative Density.	1.237 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (630.61 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.0449 mL	25.2245 mL	50.4490 mL	252.2450 mL
5 mM	1.0090 mL	5.0449 mL	10.0898 mL	50.4490 mL
10 mM	0.5045 mL	2.5224 mL	5.0449 mL	25.2245 mL
20 mM	0.2522 mL	1.2612 mL	2.5224 mL	12.6122 mL
50 mM	0.1009 mL	0.5045 mL	1.0090 mL	5.0449 mL
100 mM	0.0504 mL	0.2522 mL	0.5045 mL	2.5224 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc