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Levalbuterol tartrate

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Catalog No. T7164Cas No. 661464-94-4
Alias Levosalbutamol tartrate

Levalbuterol tartrate is a short-acting β2-adrenergic receptor agonist and the R enantiomer of salbutamol.

Levalbuterol tartrate

Levalbuterol tartrate

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Purity: 99.98%
Catalog No. T7164Alias Levosalbutamol tartrateCas No. 661464-94-4
Levalbuterol tartrate is a short-acting β2-adrenergic receptor agonist and the R enantiomer of salbutamol.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$31In StockIn Stock
5 mg$48In StockIn Stock
10 mg$85In StockIn Stock
25 mg$107In StockIn Stock
50 mg$133In StockIn Stock
100 mg$197In StockIn Stock
200 mg$288In Stock-
1 mL x 10 mM (in DMSO)$58In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.98%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Levalbuterol tartrate is a short-acting β2-adrenergic receptor agonist and the R enantiomer of salbutamol.
In vivo
METHODS: In a randomized, double-blind, placebo-controlled, three-way crossover study, 30 stable asthmatic patients received a single dose of 100 mcg of levalbuterol tartrate, 200 mcg of salbutamol, or placebo using a pMDI. Forced expiratory volume in 1 second (FEV(1)) and forced vital capacity (FVC) were measured at baseline and within 6 hours after dosing.
RESULTS Levalbuterol tartrate and salbutamol produced a significantly superior bronchodilator response to placebo. Both drugs demonstrated equivalent time-dependent bronchodilator responses as measured by the area under the curve for percent change in FEV(1) and FVC over 6 hours. The onset of action, mean maximum bronchodilator response, and duration of bronchodilator response were similar for levalbuterol tartrate and salbutamol. [2]
SynonymsLevosalbutamol tartrate
Chemical Properties
Molecular Weight389.39
FormulaC17H27NO9
Cas No.661464-94-4
SmilesO[C@H]([C@@H](O)C(O)=O)C(O)=O.CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1.CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (70.62 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5681 mL12.8406 mL25.6812 mL128.4060 mL
5 mM0.5136 mL2.5681 mL5.1362 mL25.6812 mL
10 mM0.2568 mL1.2841 mL2.5681 mL12.8406 mL
20 mM0.1284 mL0.6420 mL1.2841 mL6.4203 mL
50 mM0.0514 mL0.2568 mL0.5136 mL2.5681 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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