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Remetinostat

Name: Remetinostat
Brand: TargetMol
SKU: T16729
Rating: 4.5 (1 reviews)

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Catalog No. T16729Cas No. 946150-57-8

Alias SHP-141

Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymphoma.

Remetinostat

😃Good

Catalog No. T16729Alias SHP-141Cas No. 946150-57-8

Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymphoma.

Pack Size	Price	Availability
5 mg	$30	Backorder
10 mg	$48	Backorder
25 mg	$96	Backorder
50 mg	$156	Backorder
100 mg	$251	Backorder
1 mL x 10 mM (in DMSO)	$34	In Stock

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Product Introduction

Bioactivity

Description	Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymphoma.
Synonyms	SHP-141

Chemical Properties

Molecular Weight	323.34
Formula	C₁₆H₂₁NO₆
Cas No.	946150-57-8
Smiles	O(C(CCCCCCC(NO)=O)=O)C1=CC=C(C(OC)=O)C=C1
Relative Density.	no data available
Color	White
Appearance	solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (463.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0927 mL	15.4636 mL	30.9272 mL	154.6360 mL
5 mM	0.6185 mL	3.0927 mL	6.1854 mL	30.9272 mL
10 mM	0.3093 mL	1.5464 mL	3.0927 mL	15.4636 mL
20 mM	0.1546 mL	0.7732 mL	1.5464 mL	7.7318 mL
50 mM	0.0619 mL	0.3093 mL	0.6185 mL	3.0927 mL
100 mM	0.0309 mL	0.1546 mL	0.3093 mL	1.5464 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc