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Remetinostat (Synonyms: SHP-141)

Name: Remetinostat
Brand: TargetMol
SKU: T16729
Rating: 4.5 (1 reviews)

Catalog No. T16729 Copy Product Info

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Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymphoma.

Remetinostat

Copy Product Info

🥰Excellent

Catalog No. T16729

Synonyms SHP-141

Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymphoma.

Cas No. 946150-57-8

Pack Size	Price	USA Stock	Global Stock
5 mg	$30	Inquiry	Inquiry
10 mg	$48	Inquiry	Inquiry
25 mg	$96	Inquiry	Inquiry
50 mg	$156	Inquiry	Inquiry
100 mg	$251	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$34	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymphoma.
Synonyms	SHP-141

Chemical Properties

Molecular Weight	323.34
Formula	C₁₆H₂₁NO₆
Cas No.	946150-57-8
Smiles	O(C(CCCCCCC(NO)=O)=O)C1=CC=C(C(OC)=O)C=C1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (463.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0927 mL	15.4636 mL	30.9272 mL	154.6360 mL
5 mM	0.6185 mL	3.0927 mL	6.1854 mL	30.9272 mL
10 mM	0.3093 mL	1.5464 mL	3.0927 mL	15.4636 mL
20 mM	0.1546 mL	0.7732 mL	1.5464 mL	7.7318 mL
50 mM	0.0619 mL	0.3093 mL	0.6185 mL	3.0927 mL
100 mM	0.0309 mL	0.1546 mL	0.3093 mL	1.5464 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc