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Nicergoline

Name: Nicergoline
Brand: TargetMol
SKU: T1132
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1132Cas No. 27848-84-6

Alias Nimergoline, Nicergolinum

Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.

Nicergoline

🥰Excellent

Purity: 99.80%

Catalog No. T1132Alias Nimergoline, NicergolinumCas No. 27848-84-6

Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.

Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$38	In Stock
25 mg	$56	In Stock
50 mg	$71	In Stock
100 mg	$89	In Stock
500 mg	$219	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock

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Batch Information

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Purity:99.80%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.
Synonyms	Nimergoline, Nicergolinum

Chemical Properties

Molecular Weight	484.39
Formula	C₂₄H₂₆BrN₃O₃
Cas No.	27848-84-6
Smiles	O(C)[C@@]12C=3C=4C(C[C@]1(N(C)C[C@H](COC(=O)C=5C=C(Br)C=NC5)C2)[H])=CN(C)C4C=CC3
Relative Density.	1.47 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (103.22 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0645 mL	10.3223 mL	20.6445 mL	103.2226 mL
5 mM	0.4129 mL	2.0645 mL	4.1289 mL	20.6445 mL
10 mM	0.2064 mL	1.0322 mL	2.0645 mL	10.3223 mL
20 mM	0.1032 mL	0.5161 mL	1.0322 mL	5.1611 mL
50 mM	0.0413 mL	0.2064 mL	0.4129 mL	2.0645 mL
100 mM	0.0206 mL	0.1032 mL	0.2064 mL	1.0322 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc