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Troxerutin

Name: Troxerutin
Brand: TargetMol
SKU: T0772
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0772Cas No. 7085-55-4

Alias Trihydroxyethylrutin

Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.

Troxerutin

🥰Excellent

Purity: 99.24%

Catalog No. T0772Alias TrihydroxyethylrutinCas No. 7085-55-4

Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.

Pack Size	Price	Availability	Quantity
1 g	$29	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Batch Information

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Purity:99.24%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.
In vivo	Troxerutin contributes to the reduction of red blood cell aggregation and enhances microvascular perfusion, beneficially affecting complications of chronic venous insufficiency. It mitigates oxidative stress and cognitive impairment induced by D-galactose by lowering levels of protein carbonyl groups, reactive oxygen species, and advanced glycation end-products while also boosting the activation of PI3K/Akt. Additionally, troxerutin reduces the levels of α-aminoadipic acid, homocysteine, triglycerides, cholesterol, and low-density lipoprotein apolipoprotein B in patients with acute myocardial infarction.
Synonyms	Trihydroxyethylrutin

Chemical Properties

Molecular Weight	742.68
Formula	C₃₃H₄₂O₁₉
Cas No.	7085-55-4
Smiles	O(C1=C(OC=2C(C1=O)=C(O)C=C(OCCO)C2)C3=CC(OCCO)=C(OCCO)C=C3)[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.	1.65 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (67.32 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: 92 mg/mL (123.88 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.69 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.3465 mL	6.7324 mL	13.4647 mL	67.3237 mL
5 mM	0.2693 mL	1.3465 mL	2.6929 mL	13.4647 mL
10 mM	0.1346 mL	0.6732 mL	1.3465 mL	6.7324 mL
20 mM	0.0673 mL	0.3366 mL	0.6732 mL	3.3662 mL
50 mM	0.0269 mL	0.1346 mL	0.2693 mL	1.3465 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0135 mL	0.0673 mL	0.1346 mL	0.6732 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc