Shopping Cart

Remove All
Your shopping cart is currently empty

Hi 76-0079

Name: Hi 76-0079
Brand: TargetMol
SKU: T77659
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T77659Cas No. 374567-94-9

Alias NNC0076-0079, 76-0079

Hi 76-0079 (NNC0076-0079) is a hormone-sensitive lipase (HSL) inhibitor with an IC50 of 184 nM.Hi 76-0079 is a potential compound for the study and prevention of obesity and diabetes.

Hi 76-0079

🥰Excellent

Purity: 99.9%

Catalog No. T77659Alias NNC0076-0079, 76-0079Cas No. 374567-94-9

Hi 76-0079 (NNC0076-0079) is a hormone-sensitive lipase (HSL) inhibitor with an IC50 of 184 nM.Hi 76-0079 is a potential compound for the study and prevention of obesity and diabetes.

Pack Size	Price	Availability
1 mg	$42	In Stock
5 mg	$98	In Stock
10 mg	$147	In Stock
25 mg	$255	In Stock
50 mg	$372	In Stock
100 mg	$538	In Stock
500 mg	$1,150	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.9%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Hi 76-0079 (NNC0076-0079) is a hormone-sensitive lipase (HSL) inhibitor with an IC50 of 184 nM.Hi 76-0079 is a potential compound for the study and prevention of obesity and diabetes.
Targets&IC50	HSL:184 nM
Synonyms	NNC0076-0079, 76-0079

Chemical Properties

Molecular Weight	256.69
Formula	C₁₁H₁₃ClN₂O₃
Cas No.	374567-94-9
Smiles	O(C(NN1CCOCC1)=O)C2=CC=C(Cl)C=C2
Relative Density.	1.36 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (175.31 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (19.48 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8957 mL	19.4787 mL	38.9575 mL	194.7875 mL
5 mM	0.7791 mL	3.8957 mL	7.7915 mL	38.9575 mL
10 mM	0.3896 mL	1.9479 mL	3.8957 mL	19.4787 mL
20 mM	0.1948 mL	0.9739 mL	1.9479 mL	9.7394 mL
50 mM	0.0779 mL	0.3896 mL	0.7791 mL	3.8957 mL
100 mM	0.0390 mL	0.1948 mL	0.3896 mL	1.9479 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc