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3,4'-Dihydroxyflavone

Name: 3,4'-Dihydroxyflavone
Brand: TargetMol
SKU: T8263
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8263Cas No. 14919-49-4

3,4'-Dihydroxyflavone (3,4'-DHF) is an orally active flavonoid that exhibits antiviral activity against the Influenza A virus.

3,4'-Dihydroxyflavone

🥰Excellent

Purity: 98.33%

Catalog No. T8263Cas No. 14919-49-4

3,4'-Dihydroxyflavone (3,4'-DHF) is an orally active flavonoid that exhibits antiviral activity against the Influenza A virus.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$35	In Stock	In Stock
50 mg	$47	In Stock	-
100 mg	$66	In Stock	-
200 mg	$94	In Stock	-
1 mL x 10 mM (in DMSO)	$72	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.33%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	3,4'-Dihydroxyflavone (3,4'-DHF) is an orally active flavonoid that exhibits antiviral activity against the Influenza A virus.
In vivo	'3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily for 5 days) significantly decreases lung virus titers and pathological changes, as well as reduces body weight loss and mortality[1].
Animal Research	Animal Model: 3,4'-Dihydroxyflavone (3,4'-DHF; PO,1 mg/kg per 30 μL,daily,5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1].Dosage: 1 mg/kg per 30 μL. Administration: Oral administration daily for 5 days.

Chemical Properties

Molecular Weight	254.24
Formula	C₁₅H₁₀O₄
Cas No.	14919-49-4
Smiles	Oc1ccc(cc1)-c1oc2ccccc2c(=O)c1O
Relative Density.	1.472g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 155 mg/mL (609.66 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9333 mL	19.6665 mL	39.3329 mL	196.6646 mL
5 mM	0.7867 mL	3.9333 mL	7.8666 mL	39.3329 mL
10 mM	0.3933 mL	1.9666 mL	3.9333 mL	19.6665 mL
20 mM	0.1967 mL	0.9833 mL	1.9666 mL	9.8332 mL
50 mM	0.0787 mL	0.3933 mL	0.7867 mL	3.9333 mL
100 mM	0.0393 mL	0.1967 mL	0.3933 mL	1.9666 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc