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Jineol

Name: Jineol
Brand: TargetMol
SKU: T32291
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T32291Cas No. 178762-28-2

Alias NSC-694081, NSC694081, NSC 694081, 3,8-Quinolinediol

Jineol (NSC-694081) is a quinoline alkaloid from Scolopendra subspinipes. Jineol shows cytotoxic activity against the growth of human tumor cell lines in vitro.

Jineol

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Purity: 99.55%

Catalog No. T32291Alias NSC-694081, NSC694081, NSC 694081, 3,8-QuinolinediolCas No. 178762-28-2

Jineol (NSC-694081) is a quinoline alkaloid from Scolopendra subspinipes. Jineol shows cytotoxic activity against the growth of human tumor cell lines in vitro.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$54	-	In Stock
5 mg	$143	-	In Stock
10 mg	$228	-	In Stock
25 mg	$389	-	In Stock
50 mg	$572	-	In Stock
100 mg	$813	-	In Stock
200 mg	$1,080	-	In Stock
1 mL x 10 mM (in DMSO)	$113	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.55%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Jineol AI Summary

Jineol exhibits cytotoxicity and growth inhibition against various human tumor cell lines, including A549, SKOV3, SK-MEL-2, XF498, and HCT15 cells. It has demonstrated low effective dose (ED50) values ranging from 1.9 to 10.0 μg/ml in SRB assays and GI50 values ranging from approximately 12,823 nM to 100,000 nM in NCI human tumor cell line growth inhibition assays. These results indicate that Jineol may have potential anti-cancer properties by inhibiting cell growth across multiple cancer types, including breast, renal, non-small cell lung, leukemia, prostate, ovarian, melanoma, central nervous system, and colon cancers..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Jineol (NSC-694081) is a quinoline alkaloid from Scolopendra subspinipes. Jineol shows cytotoxic activity against the growth of human tumor cell lines in vitro.
Synonyms	NSC-694081, NSC694081, NSC 694081, 3,8-Quinolinediol

Chemical Properties

Molecular Weight	161.16
Formula	C₉H₇NO₂
Cas No.	178762-28-2
Smiles	Oc1cnc2c(O)cccc2c1
Relative Density.	1.418g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 121.25 mg/mL (752.36 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.2050 mL	31.0251 mL	62.0501 mL	310.2507 mL
5 mM	1.2410 mL	6.2050 mL	12.4100 mL	62.0501 mL
10 mM	0.6205 mL	3.1025 mL	6.2050 mL	31.0251 mL
20 mM	0.3103 mL	1.5513 mL	3.1025 mL	15.5125 mL
50 mM	0.1241 mL	0.6205 mL	1.2410 mL	6.2050 mL
100 mM	0.0621 mL	0.3103 mL	0.6205 mL	3.1025 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc