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JT010

Name: JT010
Brand: TargetMol
SKU: T15628
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T15628Cas No. 917562-33-5

JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).

JT010

🥰Excellent

Purity: 99.75%

Catalog No. T15628Cas No. 917562-33-5

JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).

Pack Size	Price	Availability
2 mg	$29	In Stock
5 mg	$48	In Stock
10 mg	$77	In Stock
25 mg	$158	In Stock
50 mg	$253	In Stock
100 mg	$377	In Stock
1 mL x 10 mM (in DMSO)	$53	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.75%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).
Targets&IC50	TRPA1:0.65 nM (EC50)

Chemical Properties

Molecular Weight	354.85
Formula	C₁₆H₁₉ClN₂O₃S
Cas No.	917562-33-5
Smiles	COCCCN(C(=O)CCl)c1nc(cs1)-c1ccc(OC)cc1
Relative Density.	1.265 g/cm3 (Predicted)
Color	Orange
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (140.9 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8181 mL	14.0905 mL	28.1809 mL	140.9046 mL
5 mM	0.5636 mL	2.8181 mL	5.6362 mL	28.1809 mL
10 mM	0.2818 mL	1.4090 mL	2.8181 mL	14.0905 mL
20 mM	0.1409 mL	0.7045 mL	1.4090 mL	7.0452 mL
50 mM	0.0564 mL	0.2818 mL	0.5636 mL	2.8181 mL
100 mM	0.0282 mL	0.1409 mL	0.2818 mL	1.4090 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc