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Thailanstatin B

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Catalog No. T205163Cas No. 1426953-23-2

Thailanstatin B is a potent pre-mRNA splicing inhibitor [IC50=6.18 μM] and exhibits antiproliferative activity.

Thailanstatin B

Thailanstatin B

😃Good
Catalog No. T205163Cas No. 1426953-23-2
Thailanstatin B is a potent pre-mRNA splicing inhibitor [IC50=6.18 μM] and exhibits antiproliferative activity.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
Thailanstatin B is a potent pre-mRNA splicing inhibitor [IC50=6.18 μM] and exhibits antiproliferative activity.
In vitro
Thailanstatin B exhibits potent antiproliferative activity against DU-145, NCI-H232A, MDA-MB-231, and SKOV-3 cells, with GI50 values ranging from 2.5 to 4.94 nM [1].
Chemical Properties
Molecular Weight572.087
FormulaC28H42ClNO9
Cas No.1426953-23-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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