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RU-TRAAK-2

Name: RU-TRAAK-2
Brand: TargetMol
SKU: T60061
Price: 74 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60061Cas No. 1210538-56-9

RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo1.

RU-TRAAK-2

🥰Excellent

Purity: 99.81%

Catalog No. T60061Cas No. 1210538-56-9

RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo1.

Pack Size	Price	Availability
1 mg	$74	In Stock
5 mg	$178	In Stock
10 mg	$278	In Stock
25 mg	$477	In Stock
50 mg	$653	In Stock
100 mg	$918	In Stock
200 mg	$1,230	In Stock
1 mL x 10 mM (in DMSO)	$190	In Stock

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Batch Information

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Purity:99.81%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo1.

Chemical Properties

Molecular Weight	335.42
Formula	C₁₉H₁₇N₃OS
Cas No.	1210538-56-9
Smiles	CN(Cc1nc2ccccc2s1)C(=O)NCC#Cc1ccccc1
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 48 mg/mL (143.10 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9813 mL	14.9067 mL	29.8134 mL	149.0668 mL
5 mM	0.5963 mL	2.9813 mL	5.9627 mL	29.8134 mL
10 mM	0.2981 mL	1.4907 mL	2.9813 mL	14.9067 mL
20 mM	0.1491 mL	0.7453 mL	1.4907 mL	7.4533 mL
50 mM	0.0596 mL	0.2981 mL	0.5963 mL	2.9813 mL
100 mM	0.0298 mL	0.1491 mL	0.2981 mL	1.4907 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc