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Anti-Mouse TNFR2 Antibody (TR75-54.7) is a monoclonal antibody targeting mouse TNFR2 that reduces white blood cell counts and decreases pro-inflammatory cytokine expression, such as CCL2 and CXCL, making it suitable for studying inflammation and cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $172 | - | In Stock | |
| 5 mg | $448 | - | In Stock | |
| 10 mg | $718 | - | In Stock | |
| 25 mg | Preferential | - | In Stock |
| Description | Anti-Mouse TNFR2 Antibody (TR75-54.7) is a monoclonal antibody targeting mouse TNFR2 that reduces white blood cell counts and decreases pro-inflammatory cytokine expression, such as CCL2 and CXCL, making it suitable for studying inflammation and cancer. |
| In vivo | Anti-Mouse TNFR2 Antibody (TR75-54.7) (200 μg; intraperitoneal injection; administered 3 days prior to 4T1 tumor cell inoculation; single dose) inhibited tumor growth and prolonged survival in female wild-type Balb/c mice bearing 4T1 tumors [1]. Anti-Mouse TNFR2 Antibody (TR75-54.7) (5 mg/kg; intraperitoneal injection; twice weekly; for 3 weeks) significantly reduced white blood cell counts in JAK2+/VF knockout C57BL/6 mice and downregulated several proinflammatory cytokines[2]. |
| Clone | TR75-54.7 |
| Reactivity | Mouse |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | TNFR2 |
| Molecular Weight | ~150 kDa |
| Isotype | Armenian Hamster IgG |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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