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CBM-301940

Name: CBM-301940
Brand: TargetMol
SKU: T68410
Price: 118 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T68410Cas No. 902146-11-6

Alias CBM301940

CBM-301940 (compound 5) is a potent and orally active MCD (Malonyl-CoA Decarboxylase) inhibitor with IC50=23 nM that improves cardiac efficiency and function with cardioprotective properties in a rat cardiac ischemia/reperfusion model.

CBM-301940

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Purity: 99.80%

Catalog No. T68410Alias CBM301940Cas No. 902146-11-6

Pack Size	Price	Availability
1 mg	$118	In Stock
5 mg	$260	In Stock
10 mg	$416	In Stock
25 mg	$710	In Stock
50 mg	$1,065	In Stock
100 mg	$1,597	In Stock

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Purity:99.80%

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COA CNMR FNMR HNMR LCMS

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Product Introduction

Bioactivity

Description	CBM-301940 (compound 5) is a potent and orally active MCD (Malonyl-CoA Decarboxylase) inhibitor with IC50=23 nM that improves cardiac efficiency and function with cardioprotective properties in a rat cardiac ischemia/reperfusion model.
Targets&IC50	Malonyl-CoA decarboxylase (MCD):23 nM
In vitro	CBM-301940 (compound 5) is a potent malonyl-CoA decarboxylase (MCD) inhibitor with oral bioactivity, exhibiting an IC₅₀ of 23 nM[1].
Alias	CBM301940

Chemical Properties

Molecular Weight	422.32
Formula	C₁₅H₂₀F₆N₂O₅
Cas No.	902146-11-6
Smiles	O=C(NC(C)CC(=O)OC(C)(C)C)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CBM-301940CBM 301940