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CBM-301940

Name: CBM-301940
Brand: TargetMol
SKU: T68410
Price: 105 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: CBM301940) Copy Product Info

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Synonyms: CBM301940

Catalog No. T68410 Copy Product Info

Purity: 99.80%

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CBM-301940 (compound 5) is a potent and orally active MCD (Malonyl-CoA Decarboxylase) inhibitor with IC50=23 nM that improves cardiac efficiency and function with cardioprotective properties in a rat cardiac ischemia/reperfusion model.

Cas No. 902146-11-6

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Pack Size	Price	USA Stock	Global Stock
1 mg	$105	-	In Stock
5 mg	$259	-	In Stock
10 mg	$415	-	In Stock
25 mg	$677	-	In Stock
50 mg	$943	-	In Stock
100 mg	$1,310	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.80%

Appearance:Viscous

Color:Transparent

Resource Download

COA CNMR FNMR HNMR LCMS

Product Introduction

Bioactivity

Description	CBM-301940 (compound 5) is a potent and orally active MCD (Malonyl-CoA Decarboxylase) inhibitor with IC50=23 nM that improves cardiac efficiency and function with cardioprotective properties in a rat cardiac ischemia/reperfusion model.
Targets & IC50	Malonyl-CoA decarboxylase (MCD):23 nM
In vitro	CBM-301940 (compound 5) is a potent malonyl-CoA decarboxylase (MCD) inhibitor with oral bioactivity, exhibiting an IC₅₀ of 23 nM[1].
Synonyms	CBM301940

Chemical Properties

Molecular Weight	422.32
Formula	C₁₅H₂₀F₆N₂O₅
Cas No.	902146-11-6
Smiles	O=C(NC(C)CC(=O)OC(C)(C)C)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F

Storage & Solubility Information

Storage

Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (236.79 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3679 mL	11.8394 mL	23.6787 mL	118.3936 mL
5 mM	0.4736 mL	2.3679 mL	4.7357 mL	23.6787 mL
10 mM	0.2368 mL	1.1839 mL	2.3679 mL	11.8394 mL
20 mM	0.1184 mL	0.5920 mL	1.1839 mL	5.9197 mL
50 mM	0.0474 mL	0.2368 mL	0.4736 mL	2.3679 mL
100 mM	0.0237 mL	0.1184 mL	0.2368 mL	1.1839 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.