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CBM-301940

Name: CBM-301940
Brand: TargetMol
SKU: T68410
Price: 105 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T68410Cas No. 902146-11-6

Alias CBM301940

CBM-301940 (compound 5) is a potent and orally active MCD (Malonyl-CoA Decarboxylase) inhibitor with IC50=23 nM that improves cardiac efficiency and function with cardioprotective properties in a rat cardiac ischemia/reperfusion model.

CBM-301940

🥰Excellent

Purity: 99.80%

Catalog No. T68410Alias CBM301940Cas No. 902146-11-6

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$105	-	In Stock
5 mg	$259	-	In Stock
10 mg	$415	-	In Stock
25 mg	$677	-	In Stock
50 mg	$943	-	In Stock
100 mg	$1,310	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.80%

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COA CNMR FNMR HNMR LCMS

Product Introduction

Bioactivity

Description	CBM-301940 (compound 5) is a potent and orally active MCD (Malonyl-CoA Decarboxylase) inhibitor with IC50=23 nM that improves cardiac efficiency and function with cardioprotective properties in a rat cardiac ischemia/reperfusion model.
Targets&IC50	Malonyl-CoA decarboxylase (MCD):23 nM
In vitro	CBM-301940 (compound 5) is a potent malonyl-CoA decarboxylase (MCD) inhibitor with oral bioactivity, exhibiting an IC₅₀ of 23 nM[1].
Synonyms	CBM301940

Chemical Properties

Molecular Weight	422.32
Formula	C₁₅H₂₀F₆N₂O₅
Cas No.	902146-11-6
Smiles	O=C(NC(C)CC(=O)OC(C)(C)C)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc