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Elevenostat

Name: Elevenostat
Brand: TargetMol
SKU: T9745
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9745Cas No. 1454902-97-6

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.

Elevenostat

🥰Excellent

Purity: 96.14%

Catalog No. T9745Cas No. 1454902-97-6

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$39	In Stock	In Stock
10 mg	$64	In Stock	In Stock
25 mg	$122	-	In Stock
50 mg	$197	-	In Stock
100 mg	$367	-	In Stock
1 mL x 10 mM (in DMSO)	$43	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:96.14%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.
Targets&IC50	HDAC11:0.235 µM
In vitro	Elevenostat induced cell death in MM cell lines[1].
In vivo	Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells[1].

Chemical Properties

Molecular Weight	315.32
Formula	C₁₆H₁₇N₃O₄
Cas No.	1454902-97-6
Smiles	COc1ccccc1NC(=O)NCc1ccc(cc1)C(=O)NO
Relative Density.	1.328 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (792.85 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (15.86 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1714 mL	15.8569 mL	31.7138 mL	158.5691 mL
5 mM	0.6343 mL	3.1714 mL	6.3428 mL	31.7138 mL
10 mM	0.3171 mL	1.5857 mL	3.1714 mL	15.8569 mL
20 mM	0.1586 mL	0.7928 mL	1.5857 mL	7.9285 mL
50 mM	0.0634 mL	0.3171 mL	0.6343 mL	3.1714 mL
100 mM	0.0317 mL	0.1586 mL	0.3171 mL	1.5857 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc