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Nifekalant hydrochloride

Name: Nifekalant hydrochloride
Brand: TargetMol
SKU: T2712
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2712Cas No. 130656-51-8

Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM. It is a Class III antiarrhythmic compound and can be used in the study of tachyarrhythmias.

Nifekalant hydrochloride

🥰Excellent

Purity: 99.91%

Catalog No. T2712Cas No. 130656-51-8

Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM. It is a Class III antiarrhythmic compound and can be used in the study of tachyarrhythmias.

Pack Size	Price	Availability
5 mg	$64	In Stock
10 mg	$89	In Stock
25 mg	$148	In Stock
50 mg	$219	In Stock

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Purity:99.91%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM. It is a Class III antiarrhythmic compound and can be used in the study of tachyarrhythmias.

Chemical Properties

Molecular Weight	441.91
Formula	C₁₉H₂₈ClN₅O₅
Cas No.	130656-51-8
Smiles	Cl.Cn1c(NCCN(CCO)CCCc2ccc(cc2)[N+]([O-])=O)cc(=O)n(C)c1=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 9 mg/mL (20.37 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2629 mL	11.3145 mL	22.6290 mL	113.1452 mL
5 mM	0.4526 mL	2.2629 mL	4.5258 mL	22.6290 mL
10 mM	0.2263 mL	1.1315 mL	2.2629 mL	11.3145 mL
20 mM	0.1131 mL	0.5657 mL	1.1315 mL	5.6573 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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