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Trotabresib

Catalog No. T36395 CAS 1706738-98-8

Synonyms: CC-90010

Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Trotabresib, CAS 1706738-98-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 98.00
5 mg	In stock	$ 247.00
10 mg	In stock	$ 397.00
25 mg	In stock	$ 663.00
50 mg	In stock	$ 945.00
100 mg	In stock	$ 1,280.00
500 mg	In stock	$ 2,570.00
1 mL * 10 mM (in DMSO)	In stock	$ 272.00

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Purity: 99.03%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.

Synonyms	CC-90010
Molecular Weight	383.46
Formula	C21H21NO4S
CAS No.	1706738-98-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45.0 mg/mL (117.4 mM), Sonication is recommended.

References and Literature

1. CELGENE QUANTICEL RESEARCH, INC. PROCESS FOR THE PREPARATION OF BROMODOMAIN INHIBITOR. Patent. WO2020023438. 2. V. Moreno, et al. CC-90010, a reversible, oral bromodomain and extra-terminal (BET) inhibitor in patients (Pts) with advanced solid tumours (STs) and relapsed/refractory (R/R) non-Hodgkin lymphoma: Updated results of a phase I study.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Cancer Active Compound Library Inhibitor Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Clinical Compound Library Histone Modification Compound Library Anti-Cancer Compound Library Bioactive Compound Library Bioactive Compounds Library Max

Related Products

Related compounds with same targets

CDD-1102 HCl BAY-850 IV-275 (S,R)-CFT8634 BET-IN-6 BRD4 Inhibitor-24 HJB97 Hexamethylene bisacetamide

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Trotabresib 1706738-98-8 Chromatin/Epigenetic Epigenetic Reader Domain CC90010 CC-90010 CC 90010 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.