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Trotabresib

Name: Trotabresib
Brand: TargetMol
SKU: T36395
Price: 84 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36395Cas No. 1706738-98-8

Alias CC-90010

Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.

Trotabresib

🥰Excellent

Purity: 99.86%

Catalog No. T36395Alias CC-90010Cas No. 1706738-98-8

Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.

Pack Size	Price	Availability
1 mg	$84	In Stock
5 mg	$198	In Stock
10 mg	$328	In Stock
25 mg	$556	In Stock
50 mg	$795	In Stock
100 mg	$1,070	In Stock
1 mL x 10 mM (in DMSO)	$226	In Stock

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Batch Information

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Purity:99.86%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.
Synonyms	CC-90010

Chemical Properties

Molecular Weight	383.46
Formula	C₂₁H₂₁NO₄S
Cas No.	1706738-98-8
Smiles	Cn1cc(-c2cc(ccc2OCC2CC2)S(C)(=O)=O)c2ccccc2c1=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45.0 mg/mL (117.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6078 mL	13.0392 mL	26.0783 mL	130.3917 mL
5 mM	0.5216 mL	2.6078 mL	5.2157 mL	26.0783 mL
10 mM	0.2608 mL	1.3039 mL	2.6078 mL	13.0392 mL
20 mM	0.1304 mL	0.6520 mL	1.3039 mL	6.5196 mL
50 mM	0.0522 mL	0.2608 mL	0.5216 mL	2.6078 mL
100 mM	0.0261 mL	0.1304 mL	0.2608 mL	1.3039 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc