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(3S,5S)-Atorvastatin (Synonyms: ent-Atorvastatin, 3S,5S-Atorvastatin)

Name: (3S,5S)-Atorvastatin
Brand: TargetMol
SKU: T21080
Rating: 4.5 (1 reviews)

Catalog No. T21080 Copy Product Info

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(3S,5S)-Atorvastatin is the inactive enantiomer of atorvastatin that has no inhibitory activity against HMG-CoA reductase but can activate the pregnane X receptor (PXR). Atorvastatin is an orally active HMG-CoA reductase inhibitor with the ability to effectively lower blood lipid levels.

(3S,5S)-Atorvastatin

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Catalog No. T21080

Synonyms ent-Atorvastatin, 3S,5S-Atorvastatin

Cas No. 501121-34-2

Pack Size	Price	USA Stock	Global Stock	Quantity
1 mg	$68	7-10 days	7-10 days
5 mg	$199	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	(3S,5S)-Atorvastatin is the inactive enantiomer of atorvastatin that has no inhibitory activity against HMG-CoA reductase but can activate the pregnane X receptor (PXR). Atorvastatin is an orally active HMG-CoA reductase inhibitor with the ability to effectively lower blood lipid levels.
Synonyms	ent-Atorvastatin, 3S,5S-Atorvastatin

Chemical Properties

Molecular Weight	558.65
Formula	C₃₃H₃₅FN₂O₅
Cas No.	501121-34-2
Smiles	C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@@H](C[C@@H](CC(O)=O)O)O)C2C(C)C)C3=CC=C(F)C=C3)C4=CC=CC=C4
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (179 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7900 mL	8.9501 mL	17.9003 mL	89.5015 mL
5 mM	0.3580 mL	1.7900 mL	3.5801 mL	17.9003 mL
10 mM	0.1790 mL	0.8950 mL	1.7900 mL	8.9501 mL
20 mM	0.0895 mL	0.4475 mL	0.8950 mL	4.4751 mL
50 mM	0.0358 mL	0.1790 mL	0.3580 mL	1.7900 mL
100 mM	0.0179 mL	0.0895 mL	0.1790 mL	0.8950 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Atorvastatin(3S,5S)Atorvastatin(3S,5S) Atorvastatin