Powder: -20°C for 3 years | In solvent: -80°C for 1 year
A2ti-2 is a low affinity and selective inhibitor of the membrane-bound protein A2/S100A10 heterotetramer (A2t) (IC50 : 230 μM).A2ti-2 exhibits antiviral activity by selectively disrupting protein interactions between A2 and S100A10, and protects against human papillomavirus type 16 (HPV16) infection.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 118.00 | |
5 mg | In stock | $ 291.00 | |
10 mg | In stock | $ 432.00 | |
25 mg | In stock | $ 715.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,360.00 | |
500 mg | In stock | $ 2,730.00 |
Description | A2ti-2 is a low affinity and selective inhibitor of the membrane-bound protein A2/S100A10 heterotetramer (A2t) (IC50 : 230 μM).A2ti-2 exhibits antiviral activity by selectively disrupting protein interactions between A2 and S100A10, and protects against human papillomavirus type 16 (HPV16) infection. |
Targets&IC50 | A2t:230 μM (IC50) |
In vitro |
A2ti-2 (compound 7a) functions as a blocker of the protein-protein interaction between annexin A2 and S100A10.[1] A2ti-2 reduction HPV16 PsV infection with <50% achieved at 100 μM. A2ti-1 decreases HPV16 entry with a 20% reduction at 100 μM.[2] |
Synonyms | A2ti-2 |
Molecular Weight | 354.43 |
Formula | C18H18N4O2S |
CAS No. | 482646-13-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (705.36 mM)
You can also refer to dose conversion for different animals. More
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A2ti-2 482646-13-9 Immunology/Inflammation Microbiology/Virology Antiviral Virus Protease A2ti2 A-2ti-2 A2ti 2 inhibitor inhibit