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Olesoxime

🥰Excellent
Catalog No. T7629Cas No. 22033-87-0
Alias TRO 19622, NSC 21311

Olesoxime (TRO 19622) (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.

Olesoxime

Olesoxime

🥰Excellent
Purity: 99.86%
Catalog No. T7629Alias TRO 19622, NSC 21311Cas No. 22033-87-0
Olesoxime (TRO 19622) (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$35-In Stock
5 mg$57-In Stock
10 mg$87-In Stock
25 mg$175-In Stock
50 mg$309-In Stock
100 mg$465-In Stock
1 mL x 10 mM (in DMSO)$63-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.86%
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Product Introduction

Bioactivity
Description
Olesoxime (TRO 19622) (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.
In vivo
Olesoxime, a molecule from a novel "cholesterol-oxime" family of cytoprotective compounds identified based on survival promoting activities on trophic factor deprived motor neurons shows neuroprotective and neuroregenerative effects in five animal models of motor nerve degeneration[1].
SynonymsTRO 19622, NSC 21311
Chemical Properties
Molecular Weight399.65
FormulaC27H45NO
Cas No.22033-87-0
SmilesCC(C)CCC[C@H](C)[C@@H]1CC[C@@H]2[C@H]3CCC4=CC(CC[C@@]4(C)[C@@H]3CC[C@@]12C)=NO
Relative Density.1.10 g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 51 mg/mL (127.61 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5022 mL12.5109 mL25.0219 mL125.1095 mL
5 mM0.5004 mL2.5022 mL5.0044 mL25.0219 mL
10 mM0.2502 mL1.2511 mL2.5022 mL12.5109 mL
20 mM0.1251 mL0.6255 mL1.2511 mL6.2555 mL
50 mM0.0500 mL0.2502 mL0.5004 mL2.5022 mL
100 mM0.0250 mL0.1251 mL0.2502 mL1.2511 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TRO-19622TRO19622OlesoximeNSC-21311NSC21311MitochondrialMetabolismMitochondrial MetabolismInhibitorinhibit
Related Tags: buy Olesoxime | purchase Olesoxime | Olesoxime cost | order Olesoxime | Olesoxime chemical structure | Olesoxime in vivo | Olesoxime formula | Olesoxime molecular weight
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