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4-Hydroxycoumarin

Name: 4-Hydroxycoumarin
Brand: TargetMol
SKU: PDK0015
Rating: 4.5 (1 reviews)

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Catalog No. PDK0015Cas No. 1076-38-6

4-Hydroxycoumarin is a coumarin derivative and one of the versatile heterocyclic scaffolds with electrophilic and nucleophilic properties.

4-Hydroxycoumarin

😃Good

Catalog No. PDK0015Cas No. 1076-38-6

4-Hydroxycoumarin is a coumarin derivative and one of the versatile heterocyclic scaffolds with electrophilic and nucleophilic properties.

Pack Size	Price	Availability	Quantity
5 g	$29	Backorder

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Batch Information

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Purity:≥98%

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description

4-Hydroxycoumarin is a coumarin derivative and one of the versatile heterocyclic scaffolds with electrophilic and nucleophilic properties.

Chemical Properties

Molecular Weight	162.14
Formula	C₉H₆O₃
Cas No.	1076-38-6
Smiles	OC1=CC(=O)OC2=CC=CC=C12
Relative Density.	1.1734 g/cm3 (Estimated)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Methanol: 20 mg/mL (123.35 mM), Sonication is recommended.

DMSO: 50 mg/mL (308.38 mM), Sonication is recommended.

Solution Preparation Table

Methanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	6.1675 mL	30.8375 mL	61.6751 mL	308.3755 mL
5 mM	1.2335 mL	6.1675 mL	12.3350 mL	61.6751 mL
10 mM	0.6168 mL	3.0838 mL	6.1675 mL	30.8375 mL
20 mM	0.3084 mL	1.5419 mL	3.0838 mL	15.4188 mL
50 mM	0.1234 mL	0.6168 mL	1.2335 mL	6.1675 mL
100 mM	0.0617 mL	0.3084 mL	0.6168 mL	3.0838 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc