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Clonixin

Name: Clonixin
Brand: TargetMol
SKU: T4542
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4542Cas No. 17737-65-4

Alias Clonixic acid

Clonixin (Clonixic acid) is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.

Clonixin

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Purity: 99.62%

Catalog No. T4542Alias Clonixic acidCas No. 17737-65-4

Pack Size	Price	Availability
1 g	$40	In Stock
5 g	$113	In Stock
10 g	$168	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.62%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Clonixin (Clonixic acid) is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.
Synonyms	Clonixic acid

Chemical Properties

Molecular Weight	262.69
Formula	C₁₃H₁₁ClN₂O₂
Cas No.	17737-65-4
Smiles	N(C1=C(C(O)=O)C=CC=N1)C2=C(C)C(Cl)=CC=C2
Relative Density.	1.3230 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Insoluble

DMSO: 50 mg/mL (190.34 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8068 mL	19.0338 mL	38.0677 mL	190.3384 mL
5 mM	0.7614 mL	3.8068 mL	7.6135 mL	38.0677 mL
10 mM	0.3807 mL	1.9034 mL	3.8068 mL	19.0338 mL
20 mM	0.1903 mL	0.9517 mL	1.9034 mL	9.5169 mL
50 mM	0.0761 mL	0.3807 mL	0.7614 mL	3.8068 mL
100 mM	0.0381 mL	0.1903 mL	0.3807 mL	1.9034 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc