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L-Alanyl-L-glutamine

Name: L-Alanyl-L-glutamine
Brand: TargetMol
SKU: T5593
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5593Cas No. 39537-23-0

Alias Ala-Gln

L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).

L-Alanyl-L-glutamine

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Purity: 99.97%

Catalog No. T5593Alias Ala-GlnCas No. 39537-23-0

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$45	In Stock	In Stock
1 mL x 10 mM (in H2O)	$53	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.97%

Color:White

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COA HNMR LCMS

Product Introduction

L-Alanyl-L-glutamine AI Summary

L-Alanyl-L-glutamine exhibits modest antiviral activity against SARS-CoV-2 by inhibiting virus-induced cytotoxicity in Caco-2 cells, with an inhibition rate of 22.74% at a concentration of 10 μM after 48 hours. It also shows inhibitory activity against the SARS-CoV-2 3CL-Pro protease at 20 μM, with inhibition percentages of 15.51% and 7.198%. In VERO-6 cells, the compound's inhibition percentages range from -0.05% to 0.35% at 10 μM after 48 hours. Additionally, L-Alanyl-L-glutamine demonstrates a minimal effect on human HDAC6 enzyme activity, with inhibitions of -3.39% and -3.55% against commercial and custom peptide substrates, respectively. Overall, it has been assessed for various bioactivities, yielding minimal inhibitory activity at the tested targets, with all assay results being above 30,000 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).
Synonyms	Ala-Gln

Chemical Properties

Molecular Weight	217.22
Formula	C₈H₁₅N₃O₄
Cas No.	39537-23-0
Smiles	[C@H](NC([C@H](C)N)=O)(CCC(N)=O)C(O)=O
Relative Density.	1.305 g/cm3 (Predicted)
Sequence	H-Ala-Gln-OH
Sequence Short	AQ

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 71.43 mg/mL (328.84 mM), Sonication is recommended.

DMSO: Insoluble

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	4.6036 mL	23.0181 mL	46.0363 mL	230.1814 mL
5 mM	0.9207 mL	4.6036 mL	9.2073 mL	46.0363 mL
10 mM	0.4604 mL	2.3018 mL	4.6036 mL	23.0181 mL
20 mM	0.2302 mL	1.1509 mL	2.3018 mL	11.5091 mL
50 mM	0.0921 mL	0.4604 mL	0.9207 mL	4.6036 mL
100 mM	0.0460 mL	0.2302 mL	0.4604 mL	2.3018 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc