Powder: -20°C for 3 years | In solvent: -80°C for 1 year
hydrocotarnine is an inhibitor of Cbl.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 169.00 | |
10 mg | In stock | $ 263.00 | |
25 mg | In stock | $ 528.00 | |
50 mg | In stock | $ 769.00 | |
100 mg | In stock | $ 1,080.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 157.00 |
Description | hydrocotarnine is an inhibitor of Cbl. |
In vivo | In vivo, inhibition of Cbl with an analgesic drug, hydrocotarnine, increases inflammasome-mediated IL-18 secretion in the colon, and protects mice from dextran sulphate sodium-induced colitis. Together, our novel findings provide new insights into the role of the SFK-Cbl axis in suppressing NLRP3 inflammasome activation and identify a novel clinical utility of hydrocortanine for disease treatment[2]. |
Molecular Weight | 221.25 |
Formula | C12H15NO3 |
CAS No. | 550-10-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (248.59 mM)
You can also refer to dose conversion for different animals. More
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hydrocotarnine 550-10-7 Others E3 ligating enzyme IL-18 NLRP3 E1/E2/E3 Enzyme inflammasome activation IL-1β Ubiquitin conjugating enzyme E1 activating enzyme inhibit Ubiquitin activating enzyme GLUT1 E2 conjugating enzyme cancer pain Ubiquitin ligase Inhibitor glycolytic metabolism glycolytic capacity cellular glucose uptake inhibitor