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TLR7/8 agonist 3

Name: TLR7/8 agonist 3
Brand: TargetMol
SKU: T13167
Price: 58 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T13167Cas No. 642473-95-8

TLR7/8 agonist 3 is a potent activator of TLR7 and TLR8.

TLR7/8 agonist 3

🥰Excellent

Purity: 99.84%

Catalog No. T13167Cas No. 642473-95-8

TLR7/8 agonist 3 is a potent activator of TLR7 and TLR8.

Pack Size	Price	Availability
1 mg	$58	In Stock
5 mg	$143	In Stock
10 mg	$238	In Stock
25 mg	$387	In Stock
50 mg	$535	In Stock
100 mg	$738	In Stock
200 mg	$993	In Stock
1 mL x 10 mM (in DMSO)	$158	In Stock

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Batch Information

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Purity:99.84%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

TLR7/8 agonist 3 is a potent activator of TLR7 and TLR8.

Chemical Properties

Molecular Weight	313.4
Formula	C₁₇H₂₃N₅O
Cas No.	642473-95-8
Smiles	CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)N
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 35 mg/mL (111.68 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1908 mL	15.9541 mL	31.9081 mL	159.5405 mL
5 mM	0.6382 mL	3.1908 mL	6.3816 mL	31.9081 mL
10 mM	0.3191 mL	1.5954 mL	3.1908 mL	15.9541 mL
20 mM	0.1595 mL	0.7977 mL	1.5954 mL	7.9770 mL
50 mM	0.0638 mL	0.3191 mL	0.6382 mL	3.1908 mL
100 mM	0.0319 mL	0.1595 mL	0.3191 mL	1.5954 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc