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Ceftiofur sodium

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Catalog No. T0198Cas No. 104010-37-9
Alias Sodium ceftiofur, Naxcel

Ceftiofur sodium (Naxcel), an antibiotic of the cephalosporin type (third generation), is used as veterinary medicine.

Ceftiofur sodium

Ceftiofur sodium

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🥰Excellent
Purity: 99.36%
Catalog No. T0198Alias Sodium ceftiofur, NaxcelCas No. 104010-37-9
Ceftiofur sodium (Naxcel), an antibiotic of the cephalosporin type (third generation), is used as veterinary medicine.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$33In StockIn Stock
100 mg$48In StockIn Stock
500 mg$98In StockIn Stock
1 g$148In StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.36%
Color:White
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Product Introduction

Ceftiofur sodium AI Summary
Ceftiofur sodium exhibits broad-spectrum antimicrobial activity against various bacterial strains, including Salmonella enterica serovars Typhimurium and Virchow, Escherichia coli (including cefoxitin-resistant and beta-lactamase-producing strains), Klebsiella pneumoniae, Citrobacter freundii, and Edwardsiella ictaluri. The minimum inhibitory concentrations (MIC) of Ceftiofur sodium range from <0.12 to 128.0 µg/mL across different strains and conditions, indicating its varying effectiveness. Additionally, the compound demonstrates inhibitory activity against mouse OAT3 with an IC50 value of 35700 nM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Ceftiofur sodium (Naxcel), an antibiotic of the cephalosporin type (third generation), is used as veterinary medicine.
SynonymsSodium ceftiofur, Naxcel
Chemical Properties
Molecular Weight545.54
FormulaC19H16N5NaO7S3
Cas No.104010-37-9
SmilesC(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CSC(=O)C4=CC=CO4)[H].[Na]
Relative Density.1.81g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 40 mg/mL (73.32 mM), Sonication is recommended.
DMSO: 240 mg/mL (439.93 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (1.83 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM1.8330 mL9.1652 mL18.3305 mL91.6523 mL
5 mM0.3666 mL1.8330 mL3.6661 mL18.3305 mL
10 mM0.1833 mL0.9165 mL1.8330 mL9.1652 mL
20 mM0.0917 mL0.4583 mL0.9165 mL4.5826 mL
50 mM0.0367 mL0.1833 mL0.3666 mL1.8330 mL
DMSO
1mg5mg10mg50mg
100 mM0.0183 mL0.0917 mL0.1833 mL0.9165 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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