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Sulfentrazone

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Catalog No. T21164Cas No. 122836-35-5
Alias FP-846

Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide

Sulfentrazone

Sulfentrazone

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Purity: 99.89%
Catalog No. T21164Alias FP-846Cas No. 122836-35-5
Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30In StockIn Stock
50 mg$40In StockIn Stock
100 mg$60In StockIn Stock
500 mg$145In StockIn Stock
1 g$213In StockIn Stock
1 mL x 10 mM (in DMSO)$45In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.89%
Color:White
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Product Introduction

Sulfentrazone AI Summary
Sulfentrazone exhibits multiple bioactivities as both a herbicide and a biochemical inhibitor. As a small molecule agonist, it targets estrogen receptor alpha signaling (potency: 35481.3 nM), glucocorticoid receptor signaling (potency: 891.3 nM), and activates the human pregnane X receptor (PXR) signaling pathway (potency: 17782.8 nM). In terms of herbicidal activity, Sulfentrazone shows significant post-emergence growth inhibition, affecting various plant species such as Eclipta prostrata, Amaranthus retroflexus, Brassica juncea, and Chenopodium album with growth inhibition (GI) ranging from 50% to 100% at dosages from 37.5 g/ha to 150 g/ha. However, Setaria faberi and grasses like Digitaria sanguinalis and Echinochloa crus-galli show lower susceptibility, with GI below 50%. Furthermore, it demonstrates inhibition of human recombinant protoporphyrinogen oxidase, indicated by a Ki value ranging from 720.0 to 724.44 nM. The compound also exhibits phytotoxic effects on crop species like Phaseolus vulgaris, Brassica napus, Gossypium hirsutum, and Zea mays, affecting parameters such as plant height, shoot dry weight, and overall yield. These varied bioactivities highlight Sulfentrazone's potential as both a herbicidal agent and a biochemical tool for studying receptor signaling and enzyme inhibition..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide
SynonymsFP-846
Chemical Properties
Molecular Weight387.19
FormulaC11H10Cl2F2N4O3S
Cas No.122836-35-5
SmilesCc1nn(-c2cc(NS(C)(=O)=O)c(Cl)cc2Cl)c(=O)n1C(F)F
Relative Density.1.72g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (71.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5827 mL12.9136 mL25.8271 mL129.1356 mL
5 mM0.5165 mL2.5827 mL5.1654 mL25.8271 mL
10 mM0.2583 mL1.2914 mL2.5827 mL12.9136 mL
20 mM0.1291 mL0.6457 mL1.2914 mL6.4568 mL
50 mM0.0517 mL0.2583 mL0.5165 mL2.5827 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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