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ELOVL6-IN-2

Name: ELOVL6-IN-2
Brand: TargetMol
SKU: T9215
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9215Cas No. 1067647-43-1

ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.

ELOVL6-IN-2

🥰Excellent

Purity: 99.43%

Catalog No. T9215Cas No. 1067647-43-1

ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.

Pack Size	Price	Availability
5 mg	$33	In Stock
10 mg	$58	In Stock
25 mg	$118	In Stock
50 mg	$223	In Stock
100 mg	$332	In Stock
200 mg	$475	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Batch Information

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Purity:99.43%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
Targets&IC50	ELOVL6:34 nM(mouse )
In vivo	ELOVL6-IN-2 potently and proportionally suppressed?the elongation index of fatty acids in the liver in mice[1].

Chemical Properties

Molecular Weight	579.49
Formula	C₂₈H₂₃F₆N₃O₄
Cas No.	1067647-43-1
Smiles	Cc1[nH]n(-c2ccc(OC(F)(F)F)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Relative Density.	1.49 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (155.31 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7257 mL	8.6283 mL	17.2566 mL	86.2828 mL
5 mM	0.3451 mL	1.7257 mL	3.4513 mL	17.2566 mL
10 mM	0.1726 mL	0.8628 mL	1.7257 mL	8.6283 mL
20 mM	0.0863 mL	0.4314 mL	0.8628 mL	4.3141 mL
50 mM	0.0345 mL	0.1726 mL	0.3451 mL	1.7257 mL
100 mM	0.0173 mL	0.0863 mL	0.1726 mL	0.8628 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc