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ZLWH-23

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Catalog No. T63560Cas No. 2765251-12-3

ZLWH-23 is a selective inhibitor of acetylcholinesterase (AChE) (IC50: 0.27 μM) and inhibits GSK-3β with an IC50 value of 6.78 μM. ZLWH-23 selectively acts on BChE (IC50=20.82 μM) and on multiple kinases as well as GSK-3β. ZLWH-23 has potential for ZLWH-23 has potential for Alzheimer's disease research.

ZLWH-23

ZLWH-23

😃Good
Catalog No. T63560Cas No. 2765251-12-3
ZLWH-23 is a selective inhibitor of acetylcholinesterase (AChE) (IC50: 0.27 μM) and inhibits GSK-3β with an IC50 value of 6.78 μM. ZLWH-23 selectively acts on BChE (IC50=20.82 μM) and on multiple kinases as well as GSK-3β. ZLWH-23 has potential for ZLWH-23 has potential for Alzheimer's disease research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5206-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
ZLWH-23 is a selective inhibitor of acetylcholinesterase (AChE) (IC50: 0.27 μM) and inhibits GSK-3β with an IC50 value of 6.78 μM. ZLWH-23 selectively acts on BChE (IC50=20.82 μM) and on multiple kinases as well as GSK-3β. ZLWH-23 has potential for ZLWH-23 has potential for Alzheimer's disease research.
Targets&IC50
AChE:0.27 μM, GSK-3β:6.78 μM
Chemical Properties
Molecular Weight513.61
FormulaC30H32FN5O2
Cas No.2765251-12-3
SmilesN(C(=O)C1CC1)C2=C3C(C=4C(N3)=CC(C(NCCC5CCN(CC6=C(F)C=CC=C6)CC5)=O)=CC4)=CC=N2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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