Shopping Cart
Remove All
Your shopping cart is currently empty
Terbogrel
Copy Product Info
😃Good
Catalog No. T17039Cas No. 149979-74-8
Alias BIBV 308SE
Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a potential compound for the prevention of blood clots.
Terbogrel
Copy Product Info😃Good
Purity: 98.95%
Catalog No. T17039Alias BIBV 308SECas No. 149979-74-8
Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a potential compound for the prevention of blood clots.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $82 | In Stock | In Stock | |
| 5 mg | $195 | In Stock | In Stock | |
| 10 mg | $285 | In Stock | In Stock | |
| 25 mg | $449 | In Stock | In Stock | |
| 50 mg | $601 | In Stock | In Stock | |
| 100 mg | $805 | In Stock | In Stock | |
| 200 mg | $1,090 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:98.95%
Appearance:Solid
Color:Yellow
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a potential compound for the prevention of blood clots. |
| Targets&IC50 | TXA2 receptor:apr 10 nM, TXA2 synthase:appr 10 nM |
| In vitro | Terbogrel inhibits collagen-induced platelet aggregation in human platelet-rich plasma and whole blood (IC50: 310 ± 18 nM (n = 8) and 52 ± 20 nM (n = 6), respectively). Terbogrel (1 μM) fully inhibits U46619-induced platelet aggregation (IC50: 10 nM). Pretreatment of platelets with terbogrel (1 μM) completely inhibits thrombin-induced thromboxane A2 formation (2±1 ng/mL) but does not result in any inhibition of platelet aggregation. Terbogrel blocks the thromboxane A2/endoperoxide receptor on washed human platelets (IC50: 11 ± 6 nM (n = 2) and IC50: 38 ± 1 nM (n = 15) in platelet-rich plasma).[1][2] |
| In vivo | Terbogrel (10 mg/kg, p.o.) is rapidly and well (90%) absorbed with a systemic availability of about 30% in rats. Terbogrel (0.1-3.0 mg/kg) shows an impressive antithrombotic efficacy in rabbits.[2] |
| Synonyms | BIBV 308SE |
| Molecular Weight | 405.49 |
| Formula | C23H27N5O2 |
| Cas No. | 149979-74-8 |
| Smiles | C(=C\CCCC(O)=O)(\C1=CC(N=C(NC(C)(C)C)NC#N)=CC=C1)/C=2C=CC=NC2 |
| Relative Density. | 1.13g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 27.5 mg/mL (67.82 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Terbogrel | purchase Terbogrel | Terbogrel cost | order Terbogrel | Terbogrel chemical structure | Terbogrel in vivo | Terbogrel in vitro | Terbogrel formula | Terbogrel molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.