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Miglitol

Name: Miglitol
Brand: TargetMol
SKU: T1529
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1529Cas No. 72432-03-2

Alias BAY-m1099, BAY1099

Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.

Miglitol

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Purity: 99.88%

Catalog No. T1529Alias BAY-m1099, BAY1099Cas No. 72432-03-2

Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 mg	$42	In Stock	-
1 g	$68	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.88%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.
In vivo	D-cycloserine (DCS) facilitates extinction of conditioned freezing to the light CS when no drug pre-exposure has occurred, but pre-exposure to DCS just prior to conditioning disrupted the facilitation of extinction effect in mice. [1] D-cycloserine (DCS) which has a high affinity for the glycine modulatory site in the NMDA receptor complex modulated memory processing in a dose-dependent manner. DCS also facilitates retention in 'senescence-accelerated mice' in which impairment of learning andmemory increases with age. [2] D-cycloserine (DCS) exhibits facilitated extinction of fear but are able to reacquire fear of that conditioned stimulus (CS) in a similar manner as saline-treated control rats. DCS-treated rats exhibits generalized extinction (i.e., they are less fearful of a non-extinguished CS) in comparison to controls. [3] D-cycloserine (DCS), an antimycobacterial agent known to cross the blood-brain barrier, binds with high affinity to this glycine modulatory site, functions as a positive modulator, and facilitates performance of learningtasks in rats. DCS appears to be a potent cognitive enhancer at doses lower than those required for antibacterial activity. [4] D-cycloserine injections (3.25, 15, or 30 mg/kg) before 30 non-reinforced light exposures dose-dependently enhances extinction but does not influence fear-potentiated startle in rats that does not receive extinction training. [5]
Synonyms	BAY-m1099, BAY1099

Chemical Properties

Molecular Weight	207.22
Formula	C₈H₁₇NO₅
Cas No.	72432-03-2
Smiles	C(CO)N1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1
Relative Density.	1.458 g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 20.7 mg/mL (99.89 mM), Sonication is recommended.

DMSO: 71.43 mg/mL (344.71 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8258 mL	24.1289 mL	48.2579 mL	241.2895 mL
5 mM	0.9652 mL	4.8258 mL	9.6516 mL	48.2579 mL
10 mM	0.4826 mL	2.4129 mL	4.8258 mL	24.1289 mL
20 mM	0.2413 mL	1.2064 mL	2.4129 mL	12.0645 mL
50 mM	0.0965 mL	0.4826 mL	0.9652 mL	4.8258 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0483 mL	0.2413 mL	0.4826 mL	2.4129 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc