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SGK1-IN-4

Name: SGK1-IN-4
Brand: TargetMol
SKU: T9977
Rating: 4.5 (1 reviews)

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Catalog No. T9977Cas No. 1628048-93-0

SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.

SGK1-IN-4

😃Good

Catalog No. T9977Cas No. 1628048-93-0

SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$113	Inquiry	Inquiry
5 mg	$278	Inquiry	Inquiry
10 mg	$396	Inquiry	Inquiry
25 mg	$645	Inquiry	Inquiry
50 mg	$868	Inquiry	Inquiry
100 mg	$1,160	Inquiry	Inquiry
200 mg	$1,560	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$335	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.

Chemical Properties

Molecular Weight	517.96
Formula	C₂₃H₂₁ClFN₅O₄S
Cas No.	1628048-93-0
Smiles	O[C@H]1CC[C@@H](CC1)Oc1nc(nc2[nH]ncc12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 245 mg/mL (473.01 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (9.65 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9307 mL	9.6533 mL	19.3065 mL	96.5326 mL
5 mM	0.3861 mL	1.9307 mL	3.8613 mL	19.3065 mL
10 mM	0.1931 mL	0.9653 mL	1.9307 mL	9.6533 mL
20 mM	0.0965 mL	0.4827 mL	0.9653 mL	4.8266 mL
50 mM	0.0386 mL	0.1931 mL	0.3861 mL	1.9307 mL
100 mM	0.0193 mL	0.0965 mL	0.1931 mL	0.9653 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc