Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 350.00 | |
5 mg | In stock | $ 970.00 | |
10 mg | In stock | $ 1,200.00 | |
25 mg | In stock | $ 1,590.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,500.00 | |
500 mg | In stock | $ 4,910.00 |
Description | DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer. |
Targets&IC50 | HER2:357 nM, DHFR:123 nM, EGFR:246 nM |
In vitro | Remarkable broad-spectrum cytotoxic potency against HepG2, MCF-7, HCT-116, PC3, and HeLa is shown by DHFR-IN-4 (compound 42) at concentrations ranging from 0 to 100 μM over a 72-hour period[1]. |
Molecular Weight | 371.46 |
Formula | C18H21N5O2S |
CAS No. | 2820126-49-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DHFR-IN-4 2820126-49-4 Cell Cycle/Checkpoint DNA Damage/DNA Repair Metabolism DHFR inhibitor inhibit