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Anti-Mouse VEGFR-2 Antibody (DC101)

Catalog No. T9901A-504 Copy Product Info
Purity: 99%
🥰Excellent
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers.

Anti-Mouse VEGFR-2 Antibody (DC101)

Copy Product Info
🥰Excellent
Catalog No. T9901A-504

Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers.

Anti-Mouse VEGFR-2 Antibody
(DC101)
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$732-4 weeks2-4 weeks
5 mgPreferential2-4 weeks2-4 weeks
10 mgPreferential2-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers.
In vivo
Methods: Anti-Mouse VEGFR-2 Antibody (DC101) (10 mg/kg, administered on days 2, 5, and 8) was injected intraperitoneally into female Balb/c mice bearing H22 tumors.
Results: Anti-Mouse VEGFR-2 Antibody (DC101) promoted tumor vascular normalization, improved tumor vascular perfusion, reduced hypoxic regions, and increased the number of CD8+ T cells within the tumor.[1]
Clone
DC101
Reactivity
Mouse
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetVEGFR2/KDR/CD309
Chemical Properties
Molecular Weight150 kDa
Antibody Information
IsotypeRat IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature | Store at -20°C | Shipping with blue ice.

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