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Anti-Mouse VEGFR-2 Antibody (DC101)
😃Good
Catalog No. T9901A-504
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers.
Anti-Mouse VEGFR-2 Antibody (DC101)
Anti-Mouse VEGFR-2 Antibody (DC101)
😃Good
Purity: 99%
Catalog No. T9901A-504
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $73 | 2-4 weeks | 2-4 weeks | |
| 5 mg | Preferential | - | In Stock | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Concentration:6.75 mg/mL
Purity:99%
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Product Introduction
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Chemical Properties
| Description | Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers. |
| In vivo | Methods: Anti-Mouse VEGFR-2 Antibody (DC101) (10 mg/kg, administered on days 2, 5, and 8) was injected intraperitoneally into female Balb/c mice bearing H22 tumors. Results: Anti-Mouse VEGFR-2 Antibody (DC101) promoted tumor vascular normalization, improved tumor vascular perfusion, reduced hypoxic regions, and increased the number of CD8+ T cells within the tumor.[1] |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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