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Anti-Mouse VEGFR-2 Antibody (DC101)
😃Good
Catalog No. T9901A-504
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers.
Anti-Mouse VEGFR-2 Antibody (DC101)
Anti-Mouse VEGFR-2 Antibody (DC101)
😃Good
Purity: 99%
Catalog No. T9901A-504
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $73 | 2-4 weeks | 2-4 weeks | |
| 5 mg | Preferential | 2-4 weeks | 2-4 weeks | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99%
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| Description | Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab. It induces tumour cell apoptosis by blocking VEGF-VEGFR binding and inhibiting tumour angiogenesis, suitable for studying colorectal and gastric cancers. |
| In vivo | Methods: Anti-Mouse VEGFR-2 Antibody (DC101) (10 mg/kg, administered on days 2, 5, and 8) was injected intraperitoneally into female Balb/c mice bearing H22 tumors. Results: Anti-Mouse VEGFR-2 Antibody (DC101) promoted tumor vascular normalization, improved tumor vascular perfusion, reduced hypoxic regions, and increased the number of CD8+ T cells within the tumor.[1] |
| Clone | DC101 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | VEGFR2/KDR/CD309 |
| Molecular Weight | 150 kDa |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Rat IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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