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mTOR inhibitor 13

Name: mTOR inhibitor 13
Brand: TargetMol
SKU: T9310
Price: 118 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9310Cas No. 1144075-44-4

mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.

mTOR inhibitor 13

🥰Excellent

Purity: 99.75%

Catalog No. T9310Cas No. 1144075-44-4

mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.

Pack Size	Price	Availability
1 mg	$118	In Stock
5 mg	$287	In Stock
10 mg	$392	In Stock
25 mg	$593	In Stock
50 mg	$798	In Stock
100 mg	$1,050	In Stock
200 mg	$1,420	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.75%

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COA LCMS LCMS HNMR

Product Introduction

Bioactivity

Description	mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.
Targets&IC50	PI3Kα:119nM, mTOR:0.29nM
In vitro	mTOR inhibitor 13 inhibits the growth of LNCaP cell with IC50 of 27nM[1].

Chemical Properties

Molecular Weight	458.54
Formula	C₂₄H₂₂N₆O₂S
Cas No.	1144075-44-4
Smiles	N(C(NC=1C=CC=NC1)=O)C2=CC=C(C3=NC(=C4C(=N3)C=CS4)N5CC6OC(C5)CC6)C=C2
Relative Density.	1.440 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (98.14 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1808 mL	10.9042 mL	21.8083 mL	109.0417 mL
5 mM	0.4362 mL	2.1808 mL	4.3617 mL	21.8083 mL
10 mM	0.2181 mL	1.0904 mL	2.1808 mL	10.9042 mL
20 mM	0.1090 mL	0.5452 mL	1.0904 mL	5.4521 mL
50 mM	0.0436 mL	0.2181 mL	0.4362 mL	2.1808 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc