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Furagin
🥰Excellent
Catalog No. T4273Cas No. 1672-88-4
Alias NF-416, Furazidine, Furazidin, F-35, Akritoin
Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections.
Furagin
🥰Excellent
Purity: 99.28%
Catalog No. T4273Alias NF-416, Furazidine, Furazidin, F-35, AkritoinCas No. 1672-88-4
Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $35 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock |
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Purity:99.28%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections. |
| Targets&IC50 | CA IX (human):260 nM (Ki), CA XII (human):57 nM (Ki) |
| In vitro | The furagin concentrations in serum remain several hours above the MIC concentrations of many pathogenic bacteria. Despite the high concentrations in serum, the urine levels of furagin were generally lower than those of nitrofurantoin. The 24 hr recoveries in urine were 8--13% for furagin and about 36% for nitrofurantoin. |
| In vivo | A time-independent increase in SCE frequency was found in lymphocytes of children treated with furagin. Total CA frequency did not differ significantly between groups of children with various duration of furagin treatment. |
| Synonyms | NF-416, Furazidine, Furazidin, F-35, Akritoin |
| Molecular Weight | 264.19 |
| Formula | C10H8N4O5 |
| Cas No. | 1672-88-4 |
| Smiles | [O-][N+](=O)c1ccc(\C=C\C=N\N2CC(=O)NC2=O)o1 |
| Relative Density. | 1.61 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (37.85 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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