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EMD638683 R-Form

Name: EMD638683 R-Form
Brand: TargetMol
SKU: T11181
Rating: 4.5 (1 reviews)

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Catalog No. T11181Cas No. 1184940-47-3

EMD638683 is a highly selective SGK1 inhibitor with an IC50 of 3 μM. EMD638683 (R-Form) is the R-form of this compound.

EMD638683 R-Form

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Catalog No. T11181Cas No. 1184940-47-3

EMD638683 is a highly selective SGK1 inhibitor with an IC50 of 3 μM. EMD638683 (R-Form) is the R-form of this compound.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$193	5 days	5 days
5 mg	$327	5 days	5 days
25 mg	$766	8-10 weeks	8-10 weeks
50 mg	$996	8-10 weeks	8-10 weeks
100 mg	$1,750	8-10 weeks	8-10 weeks
1 mL x 10 mM (in DMSO)	$358	5 days	5 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description

EMD638683 is a highly selective SGK1 inhibitor with an IC50 of 3 μM. EMD638683 (R-Form) is the R-form of this compound.

Chemical Properties

Molecular Weight	364.34
Formula	C₁₈H₁₈F₂N₂O₄
Cas No.	1184940-47-3
Relative Density.	1.363 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 180 mg/mL (494.04 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7447 mL	13.7234 mL	27.4469 mL	137.2345 mL
5 mM	0.5489 mL	2.7447 mL	5.4894 mL	27.4469 mL
10 mM	0.2745 mL	1.3723 mL	2.7447 mL	13.7234 mL
20 mM	0.1372 mL	0.6862 mL	1.3723 mL	6.8617 mL
50 mM	0.0549 mL	0.2745 mL	0.5489 mL	2.7447 mL
100 mM	0.0274 mL	0.1372 mL	0.2745 mL	1.3723 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc