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MV151
(Synonyms: MV 151) Copy Product Info
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Synonyms: MV 151
Catalog No. T68275 Copy Product Info
🥰Excellent
MV151 is a fluorescent dye and a proteasome inhibitor with cell permeability, capable of specifically targeting all active subunits of proteasomes and immunoproteasomes in living cells. Used for in vitro and in vivo proteasome labeling and functional studies.
Cas No. 945611-88-1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $1,450 | - | In Stock | |
| 5 mg | $2,930 | - | In Stock | |
| 10 mg | $3,950 | - | In Stock | |
| 25 mg | Inquiry | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
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Purity:>99.99%
ee:100%
Appearance:Solid
Color:Red
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | MV151 is a fluorescent dye and a proteasome inhibitor with cell permeability, capable of specifically targeting all active subunits of proteasomes and immunoproteasomes in living cells. Used for in vitro and in vivo proteasome labeling and functional studies. |
| In vitro | Methods: In EL-4 and HeLa cell lysates, MV151 was incubated at concentrations from 10 nM to 10 μM for 1 hour, followed by proteasome labeling and gel detection. Results: MV151 uniformly labeled all active subunits (β1, β2, β5), with detection possible at 10 nM and saturation at 1 μM, showing sensitivity more than 3-fold higher than silver staining.[1] |
| In vivo | Methods: In C57Bl/6 and UbG76V-GFP transgenic mice, a single intraperitoneal injection of MV151 (20 μmol/kg, solvent 60% DMSO/40% PBS) was administered, and detection was performed 24 h later. Results: Significant fluorescent labeling was observed in the liver and pancreas, consistent with GFP reporter accumulation, confirming that MV151 effectively labels and inhibits the proteasome in vivo.[1] |
| Synonyms | MV 151 |
| Molecular Weight | 1137.28 |
| Formula | C59H91BF2N8O9S |
| Cas No. | 945611-88-1 |
| Smiles | O=C(CCC1=C(C)N2[B-](F)(F)[N+]3=C(C4=CC=C(OC)C=C4)C=CC3=CC2=C1C)NCCCCCC(NCCCCCC(NCCCCCC(NC(CC(C)C)C(NC(CC(C)C)C(NC(CC(C)C)C=CS(=O)(C)=O)=O)=O)=O)=O)=O |
| Storage | Keep away from direct sunlight,Keep away from moisture,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
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Related Tags: MV151 chemical structure | MV151 in vivo | MV151 in vitro | MV151 formula | MV151 molecular weight
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