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Tributyrin

Name: Tributyrin
Brand: TargetMol
SKU: T19676
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19676Cas No. 60-01-5

Alias NSC-661583, NSC661583, NSC 661583

Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.

Tributyrin

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Purity: 97.01%

Catalog No. T19676Alias NSC-661583, NSC661583, NSC 661583Cas No. 60-01-5

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 mL	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:97.01%

Appearance:Liquid

Color:Transparent

Resource Download

COA LCMS GC HNMR

Product Introduction

Bioactivity

Description	Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.
Synonyms	NSC-661583, NSC661583, NSC 661583

Chemical Properties

Molecular Weight	302.36
Formula	C₁₅H₂₆O₆
Cas No.	60-01-5
Smiles	CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC
Relative Density.	1.032g/mLat 20°C(lit.)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (330.73 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3073 mL	16.5366 mL	33.0732 mL	165.3658 mL
5 mM	0.6615 mL	3.3073 mL	6.6146 mL	33.0732 mL
10 mM	0.3307 mL	1.6537 mL	3.3073 mL	16.5366 mL
20 mM	0.1654 mL	0.8268 mL	1.6537 mL	8.2683 mL
50 mM	0.0661 mL	0.3307 mL	0.6615 mL	3.3073 mL
100 mM	0.0331 mL	0.1654 mL	0.3307 mL	1.6537 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc