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RS-25344

🥰Excellent
Catalog No. T9239Cas No. 152814-89-6

RS-25344 is a potent and selective phosphodiesterase (PDE) 4 inhibitor. It inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro.

RS-25344
Other Forms of RS-25344:
RS-25344 hydrochlorideT23256152815-28-6
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RS-25344

🥰Excellent
Purity: 98.98%
Catalog No. T9239Cas No. 152814-89-6
RS-25344 is a potent and selective phosphodiesterase (PDE) 4 inhibitor. It inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$80In StockIn Stock
5 mg$181In StockIn Stock
10 mg$272In StockIn Stock
25 mg$448In StockIn Stock
50 mg$630In StockIn Stock
100 mg$852In StockIn Stock
200 mg$1,130In StockIn Stock
1 mL x 10 mM (in DMSO)$197In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.98%
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Product Introduction

Bioactivity
Description
RS-25344 is a potent and selective phosphodiesterase (PDE) 4 inhibitor. It inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro.
Targets&IC50
PDE4:0.28 nM, PDE1:100 nM, PDE2:160 nM, PDE3:330 nM
Chemical Properties
Molecular Weight375.34
FormulaC19H13N5O4
Cas No.152814-89-6
SmilesO=C1N(C=2C(C(=O)N1CC=3C=CN=CC3)=CC=CN2)C4=CC(N(=O)=O)=CC=C4
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (133.21 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6643 mL13.3213 mL26.6425 mL133.2126 mL
5 mM0.5329 mL2.6643 mL5.3285 mL26.6425 mL
10 mM0.2664 mL1.3321 mL2.6643 mL13.3213 mL
20 mM0.1332 mL0.6661 mL1.3321 mL6.6606 mL
50 mM0.0533 mL0.2664 mL0.5329 mL2.6643 mL
100 mM0.0266 mL0.1332 mL0.2664 mL1.3321 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

RS-25344RS25344RS 25344PDE4PDE3PDE2PDE1
Related Tags: buy RS-25344 | purchase RS-25344 | RS-25344 cost | order RS-25344 | RS-25344 chemical structure | RS-25344 formula | RS-25344 molecular weight
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