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Fmoc-THR(GalNAc(Ac)3-α-D)-OH
(Synonyms: Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OH) Copy Product Info
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Synonyms: Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OH
Catalog No. TP1166 Copy Product Info
Purity: 98.13%
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Fmoc-THR(GalNAc(Ac)3-α-D)-OH is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. Fmoc-THR(GalNAc(Ac)3-α-D)-OH is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.
Cas No. 116783-35-8
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 mg | $39 | In Stock | In Stock | |
| 10 mg | $58 | In Stock | In Stock | |
| 25 mg | $98 | In Stock | In Stock | |
| 50 mg | $170 | In Stock | In Stock | |
| 100 mg | $258 | In Stock | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.13%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Fmoc-THR(GalNAc(Ac)3-α-D)-OH is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. Fmoc-THR(GalNAc(Ac)3-α-D)-OH is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates. |
| In vitro | The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn antigen)[1]. |
| Synonyms | Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OH |
| Molecular Weight | 670.66 |
| Formula | C33H38N2O13 |
| Cas No. | 116783-35-8 |
| Smiles | CC(OC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1NC(C)=O)C(NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O |
| Relative Density. | 1.38 g/cm3 |
| Sequence | Fmoc-Thr(GalNAc(Ac)3-|A-D)-OH |
| Sequence Short | T |
| Storage | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: soluble |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Related Tags: Fmoc-THR(GalNAc(Ac)3-α-D)-OH chemical structure | Fmoc-THR(GalNAc(Ac)3-α-D)-OH in vitro | Fmoc-THR(GalNAc(Ac)3-α-D)-OH formula | Fmoc-THR(GalNAc(Ac)3-α-D)-OH molecular weight
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