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ZINC77292789
🥰Excellent
Catalog No. TP1166Cas No. 116783-35-8
Alias Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OH
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.
ZINC77292789
🥰Excellent
Purity: 99.24%
Catalog No. TP1166Alias Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OHCas No. 116783-35-8
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $39 | In Stock | |
| 10 mg | $58 | In Stock | |
| 25 mg | $98 | In Stock | |
| 50 mg | $170 | In Stock | |
| 100 mg | $258 | In Stock |
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Purity:99.24%
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Product Introduction
Bioactivity
Chemical Properties
| Description | ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates. |
| In vitro | The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn antigen)[1]. |
| Synonyms | Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OH |
| Molecular Weight | 670.66 |
| Formula | C33H38N2O13 |
| Cas No. | 116783-35-8 |
| Smiles | CC(OC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1NC(C)=O)C(NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O |
| Relative Density. | 1.38 g/cm3 |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: soluble |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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