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Hexylglutathione

Name: Hexylglutathione
Brand: TargetMol
SKU: T27541
Rating: 4.5 (1 reviews)

(Synonyms: Hexylglutathione) Copy Product Info

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Synonyms: Hexylglutathione

Catalog No. T27541 Copy Product Info

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S-Hexylglutathione is an S-substituted glutathione derivative, in which the hydrogen atom on the thiol group of glutathione is replaced by a hexyl group. It competitively inhibits glutathione-S-transferase and can also be used as an affinity chromatography ligand for glutathione-S-transferase and glutathione peroxidase.

Cas No. 24425-56-7

Pack Size	Price	USA Stock	Global Stock
100 mg	$287	35 days	35 days
250 mg	$613	35 days	35 days
500 mg	$1,130	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	S-Hexylglutathione is an S-substituted glutathione derivative, in which the hydrogen atom on the thiol group of glutathione is replaced by a hexyl group. It competitively inhibits glutathione-S-transferase and can also be used as an affinity chromatography ligand for glutathione-S-transferase and glutathione peroxidase.
In vitro	Methods: Affinity binding assays were used to determine the binding affinity of S-Hexylglutathione to human glutathione transferase P1‑1 (wild-type and Y49F mutant). Results: S-Hexylglutathione can specifically bind to human glutathione transferase P1‑1: 1.The dissociation constant Kd for the Y49F mutant was 3.7 μM. 2.The dissociation constant Kd for the wild type was 1.27 μM [1].
Synonyms	Hexylglutathione

Chemical Properties

Molecular Weight	391.48
Formula	C₁₆H₂₉N₃O₆S
Cas No.	24425-56-7
Smiles	[C@H](C(NCC(O)=O)=O)(NC(CC[C@@H](C(O)=O)N)=O)CSCCCCCC
Relative Density.	1.31g/cm3
Sequence	H-γGlu-Cys(hexyl)-Gly-OH
Sequence Short	ECG

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (25.54 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5544 mL	12.7720 mL	25.5441 mL	127.7204 mL
5 mM	0.5109 mL	2.5544 mL	5.1088 mL	25.5441 mL
10 mM	0.2554 mL	1.2772 mL	2.5544 mL	12.7720 mL
20 mM	0.1277 mL	0.6386 mL	1.2772 mL	6.3860 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.